大学卒業後は研修医期間を経て大学院へ進学、現在まで一貫して 失明につながる網膜疾患に関する研究を継続しています。

研究業績　2020～

視神経変性疾患の病態解明と治療研究.
原田知加子、行方和彦、郭　暁麗、原田高幸. 日本薬理学雑誌（印刷中）

Monogenic gene therapy for glaucoma and optic nerve injury. Neural Regeneration Research 2025
Harada C, Guo X, Harada T.

Asking one mechanism in glial cells during neuroinflammation. Neural Regeneration Research 2025
Guo X, Harada C, Harada T.

Drug combination of topical ripasudil and brimonidine enhances neuroprotection in a mouse model of optic nerve injury. Journal of Pharmacological Sciences 2024
Namekata K, Noro T, Nishijima E, Sotozono A, Guo X, Harada C, Shinozaki Y, Mitamura Y, Nakano T, Harada T.

Membrane-anchored intracellular insulin receptor elicits ligand independent downstream signaling. Biochemistry and Biophysics Reports 2024
Sotozono A, Namekata K, Guo X, Shinozaki Y, Harada C, Noro T, Nakano T, Harada T.

Neuroprotection and axon regeneration by novel low-molecular-weight compounds through the modification of DOCK3 conformation. Cell Death Discovery 2023
Namekata K, Tsuji N, Guo X, Nishijima E, Honda S, Kitamura Y, Yamasaki A, Kishida M, Takeyama J, Ishikawa H, Shinozaki Y, Kimura A, Harada C, Harada T.

Vision protection and robust axon regeneration in glaucoma models by membrane-associated Trk receptors. Molecular Therapy 2023
Nishijima E, Honda S, Kitamura Y, Namekata K, Kimura A, Guo X, Azuchi Y, Harada C, Murakami A, Matsuda A, Nakano T, Parada LF, Harada T.

Effects of constitutively active K-Ras on axon regeneration after optic nerve injury. Neuroscience Letters 2023
Kiyota N, Namekata K, Nishijima E, Guo X, Kimura A, Harada C, Nakazawa T, Harada T.

ASK1 signaling regulates phase specific glial interactions during neuroinflammation. Proc Natl Acad Sci U S A. 2022
Guo X, Kimura A, Namekata K, Harada C, Arai N, Takeda K, Ichijo H, Harada T.

Effects of lighting environment on the degeneration of retinal ganglion cells in glutamate/aspartate transporter deficient mice, a mouse model of normal tension glaucoma. Biochemistry and Biophysics Reports 2022
Ohashi T, Namekata K, Guo X, Kimura A, Harada C, Harada T.

Topical ripasudil stimulates neuroprotection and axon regeneration in adult mice following optic nerve injury. Scientific Reports 2020
Nishijima E, Namekata K, Kimura A, Guo X, Harada C, Noro T, Nakano T, Harada T.

Suppression of oxidative stress as potential therapeutic approach for normal tension glaucoma. Antioxidants 2020
Harada C, Noro T, Kimura A, Guo X, Namekata K, Nakano T, Harada, T.

Roles of the DOCK-D family proteins in a mouse model of neuroinflammation. J Biol Chem. 2020　Namekata K, Guo X, Kimura A, Azuchi Y, Kitamura Y, Harada C, Harada T.

研究業績　2012～2019

Normal tension glaucoma-like degeneration of the visual system in aged marmosets. Sci Rep. 2019　Noro T, Namekata K, Kimura A, Azuchi Y, Hashimoto N, Moriya-Ito K, Komaki Y, Lee CY, Okahara N, Guo X, Harada C, Kim E, Nakano T, Tsuneoka H, Inoue T, Sasaki E, Tokuno H, Harada T.

Survival of Alpha and Intrinsically Photosensitive Retinal Ganglion Cells in NMDA-Induced Neurotoxicity and a Mouse Model of Normal Tension Glaucoma. Invest Ophthalmol Vis Sci. 2019　Honda S, Namekata K, Kimura A, Guo X, Harada C, Murakami A, Matsuda A, Harada T.

DOCK8 is expressed in microglia, and it regulates microglial activity during neurodegeneration in murine disease models. J Biol Chem. 2019　Namekata K, Guo X, Kimura A, Arai N, Harada C, Harada T.

Differential effects of N-acetylcysteine on retinal degeneration in two mouse models of normal tension glaucoma. Cell Death Dis. 2019　Sano H, Namekata K, Kimura A, Shitara H, Guo X, Harada C, Mitamura Y, Harada T.

Recent advances in genetically modified animal models of glaucoma and their roles in drug repositioning. Br J Ophthalmol. 2019　Harada C, Kimura A, Guo X, Namekata K, Harada T.

Role of neuritin in retinal ganglion cell death in adult mice following optic nerve injury. Sci Rep. 2018　Azuchi Y, Namekata K, Shimada T, Guo X, Kimura A, Harada C, Saito A, Yamagata K, Harada T.

Topical Ripasudil Suppresses Retinal Ganglion Cell Death in a Mouse Model of Normal Tension Glaucoma. Invest Ophthalmol Vis Sci. 2018　Akaiwa K, Namekata K, Azuchi Y, Sano H, Guo X, Kimura A, Harada C, Mitamura Y, Harada T.

Edaravone Prevents Retinal Degeneration in Adult Mice Following Optic Nerve Injury. Invest Ophthalmol Vis Sci. 2017　Akiyama G, Azuchi Y, Guo X, Noro T, Kimura A, Harada C, Namekata K, Harada T.

The Renin-Angiotensin System Regulates Neurodegeneration in a Mouse Model of Optic Neuritis. Am J Pathol. 2017　Guo X, Namekata K, Kimura A, Harada C, Harada T.

ASK1 in neurodegeneration. Adv Biol Regul. 2017　Guo X, Namekata K, Kimura A, Harada C, Harada T.

Edaravone suppresses retinal ganglion cell death in a mouse model of normal tension glaucoma. Cell Death Dis. 2017　Akaiwa K, Namekata K, Azuchi Y, Guo X, Kimura A, Harada C, Mitamura Y, Harada T.

Targeting Oxidative Stress for Treatment of Glaucoma and Optic Neuritis. Oxid Med Cell Longev. 2017　Kimura A, Namekata K, Guo X, Noro T, Harada C, Harada T.

Valproic acid and ASK1 deficiency ameliorate optic neuritis and neurodegeneration in an animal model of multiple sclerosis. Neurosci Lett. 2017　Azuchi Y, Kimura A, Guo X, Akiyama G, Noro T, Harada C, Nishigaki A, Namekata K, Harada T.

Caloric restriction promotes cell survival in a mouse model of normal tension glaucoma. Sci Rep. 2016　Guo X, Kimura A, Azuchi Y, Akiyama G, Noro T, Harada C, Namekata K, Harada T.

Neuroprotection, Growth Factors and BDNF-TrkB Signalling in Retinal Degeneration. Int J Mol Sci. 2016　Kimura A, Namekata K, Guo X, Harada C, Harada T.

Dock3-NMDA receptor interaction as a target for glaucoma therapy. Histol Histopathol. 2017　Kimura A, Namekata K, Guo X, Harada C, Harada T.

TrkB Signaling in Retinal Glia Stimulates Neuroprotection after Optic Nerve Injury. Am J Pathol. 2015　Harada C, Azuchi Y, Noro T, Guo X, Kimura A, Namekata K, Harada T.

Spermidine Ameliorates Neurodegeneration in a Mouse Model of Normal Tension Glaucoma. Invest Ophthalmol Vis Sci. 2015　Noro T, Namekata K, Azuchi Y, Kimura A, Guo X, Harada C, Nakano T, Tsuneoka H, Harada T.

Spermidine promotes retinal ganglion cell survival and optic nerve regeneration in adult mice following optic nerve injury. Cell Death Dis. 2015 Noro T, Namekata K, Kimura A, Guo X, Azuchi Y, Harada C, Nakano T, Tsuneoka H, Harada T.

Brimonidine suppresses loss of retinal neurons and visual function in a murine model of optic neuritis. Neurosci Lett. 2015　Guo X, Namekata K, Kimura A, Noro T, Azuchi Y, Semba K, Harada C, Yoshida H, Mitamura Y, Harada T.

Valproic acid prevents retinal degeneration in a murine model of normal tension glaucoma. Neurosci Lett. 2015　Kimura A, Guo X, Noro T, Harada C, Tanaka K, Namekata K, Harada T.

Valproic acid prevents NMDA-induced retinal ganglion cell death via stimulation of neuronal TrkB receptor signaling. Am J Pathol. 2015　Kimura A, Namekata K, Guo X, Noro T, Harada C, Harada T.

Expression of intraocular peroxisome proliferator-activated receptor gamma in patients with proliferative diabetic retinopathy.　J Diabetes Complications. 2015　Katome T, Namekata K, Mitamura Y, Semba K, Egawa M, Naito T, Harada C, Harada T.

Dock3 overexpression and p38 MAPK inhibition synergistically stimulate neuroprotection and axon regeneration after optic nerve injury.　Neurosci Lett. 2014　Semba K, Namekata K, Kimura A, Harada C, Katome T, Yoshida H, Mitamura Y, Harada T.

Neurotrophic factors.
Harada C, Harada T.
In: Neuroprotection and Neuroregeneration for Retinal Diseases. Springer Japan
(Toru Nakazawa, Yasushi Kitaoka, Takayuki Harada, eds.)

Dock3 protects myelin in the cuprizone model for demyelination. Cell Death Dis. 2014
Namekata K, Kimura A, Harada C, Yoshida H, Matsumoto Y, Harada T.

Dock GEFs and their therapeutic potential: Neuroprotection and axon regeneration.
Namekata K, Kimura A, Kawamura K, Harada C, Harada T. Prog Retin Eye Res. 2014

Brimonidine prevents neurodegeneration in a mouse model of normal tension glaucoma.
Semba K, Namekata K, Kimura A, Harada C, Mitamura Y, Harada T. Cell Death Dis. 2014

Renin-angiotensin system regulates neurodegeneration in a mouse model of normal tension glaucoma.
Semba K, Namekata K, Guo X, Harada C, Harada T, Mitamura Y. Cell Death Dis. 2014

「神経系のMAPキナーゼ」網膜変性疾患とMAPキナーゼ.　
原田知加子、原田高幸.　Clinical Neuroscience. 2013

Dock3 attenuates neural cell death due to NMDA neurotoxicity and oxidative stress in a mouse model of normal tension glaucoma.
Namekata K, Kimura A, Kawamura K, Guo X, Harada C, Tanaka K, Harada T. Cell Death Differ. 2013

Inhibition of ASK1-p38 pathway prevents neural cell death following optic nerve injury.
Katome T, Namekata K, Guo X, Semba K, Kittaka D, Kawamura K, Kimura A, Harada C, Ichijo H, Mitamura Y, Harada T. Cell Death Differ. 2013


Expression of promyelocytic leukemia protein and vascular endothelial growth factor in aqueous humor and vitreous fluid in patients with proliferative diabetic retinopathy.
Katome T, Namekata K, Naito T, Semba K, Guo X, Harada C, Harada T, Mitamura Y. Diabetes Res Clin Pract. 2012

Dock3 regulates BDNF-TrkB signaling for neurite outgrowth by forming a ternary complex with Elmo and RhoG. Namekata K, Watanabe H, Guo X, Kittaka D, Kawamura K, Kimura A, Harada C, Harada T. Genes Cells. 2012

Dock3 stimulates axonal outgrowth via GSK-3β-mediated microtubule assembly.
Namekata K, Harada C, Guo X, Kimura A, Kittaka D, Watanabe H, Harada T. J Neurosci. 2012

Expression of promyelocytic leukemia protein and vascular endothelial growth factor in aqueous humor and vitreous fluid in patients with proliferative diabetic retinopathy.Katome T, Namekata K, Naito T, Semba K, Guo X, Harada C, Harada T, Mitamura Y.　Diabetes Res Clin Pract. 2012

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研究業績　1997～2011

Glia- and neuron-specific functions of TrkB signalling during retinal degeneration and regeneration.
Harada C, Guo X, Namekata K, Kimura A, Nakamura K, Tanaka K, Parada LF, Harada T. Nat Commun. 2011

Spermidine alleviates severity of murine experimental autoimmune encephalomyelitis.
Guo X, Harada C, Namekata K, Kimura A, Mitamura Y, Yoshida H, Matsumoto Y, Harada T. Invest Ophthalmol Vis Sci. 2011

Regulation of the severity of neuroinflammation and demyelination by TLR-ASK1-p38 pathway.
Guo X, Harada C, Namekata K, Matsuzawa A, Camps M, Ji H, Swinnen D, Jorand-Lebrun C, Muzerelle M, Vitte PA, Rückle T, Kimura A, Kohyama K, Matsumoto Y, Ichijo H, Harada T. EMBO Mol Med. 2010

Delayed onset of experimental autoimmune encephalomyelitis in Olig1 deficient mice.
Guo X, Harada C, Namekata K, Mitamura Y, Yoshida H, Matsumoto Y, Harada T. PLoS One. 2010

ASK1 deficiency attenuates neural cell death in GLAST-deficient mice, a model of normal tension glaucoma.
Harada C, Namekata K, Guo X, Yoshida H, Mitamura Y, Matsumoto Y, Tanaka K, Ichijo H, Harada T. Cell Death Differ. 2010

Dock3 induces axonal outgrowth by stimulating membrane recruitment of the WAVE complex.
Namekata K, Harada C, Taya C, Guo X, Kimura H, Parada LF, Harada T. Proc Natl Acad Sci U S A. 2010

Expression of NG2-positive cells during optic neuritis.
Nakamura K, Guo X, Harada C, Mitamura Y, Matsumoto Y, Harada T. Jpn J Ophthalmol. 2010

Transcription factor, SP1, in epiretinal membranes of patients with proliferative diabetic retinopathy.
Yoshida-Hata N, Mitamura Y, Oshitari T, Namekata K, Harada C, Harada T, Yamamoto S. Diabetes Res Clin Pract. 2010

Interleukin-1 attenuates normal tension glaucoma-like retinal degeneration in EAAC1-deficient mice.
Namekata K, Harada C, Guo X, Kikushima K, Kimura A, Fuse N, Mitamura Y, Kohyama K, Matsumoto Y, Tanaka K, Harada T. Neurosci Lett. 2009 Nov 13;465(2):160-4. Epub 2009

Effect of geranylgeranylacetone on optic neuritis in experimental autoimmune encephalomyelitis.
Guo X, Harada C, Namekata K, Kikushima K, Mitamura Y, Yoshida H, Matsumoto Y, Harada T. Neurosci Lett. 2009

Interleukin-1 stimulates glutamate uptake in glial cells by accelerating membrane trafficking of Na+/K+-ATPase via actin depolymerization.
Namekata K, Harada C, Kohyama K, Matsumoto Y, Harada T. Mol Cell Biol. 2008 May;28(10):3273-80. Epub 2008

Role of cytokines and trophic factors in the pathogenesis of diabetic retinopathy.
Mitamura Y, Harada C, Harada T. Curr Diabetes Rev. 2005

Inhibition of glial cell activation ameliorates the severity of experimental autoimmune encephalomyelitis.
Guo X, Nakamura K, Kohyama K, Harada C, Behanna HA, Watterson DM, Matsumoto Y, Harada T. Neurosci Res. 2007

Neuroprotective effect of geranylgeranylacetone against ischemia-induced retinal injury.
Harada C, Nakamura K, Guo X, Kitaichi N, Mitamura Y, Yoshida K, Ohno S, Yoshida H, Harada T. Mol Vis. 2007

The potential role of glutamate transporters in the pathogenesis of normal tension glaucoma.
Harada T, Harada C, Nakamura K, Quah HM, Okumura A, Namekata K, Saeki T, Aihara M, Yoshida H, Mitani A, Tanaka K. J Clin Invest. 2007

Glycated albumin induces activation of activator protein-1 in retinal glial cells.
Okumura A, Mitamura Y, Namekata K, Nakamura K, Harada C, Harada T. Jpn J Ophthalmol. 2007

Intracellular sortilin expression pattern regulates proNGF-induced naturally occurring cell death during development. Nakamura K, Namekata K, Harada C, Harada T. Cell Death Differ. 2007 Aug;14(8):1552-4. Epub 2007

Molecular regulation of visual system development: more than meets the eye.
Harada T, Harada C, Parada LF. Genes Dev. 2007

Effect of photoreceptor degeneration on RNA splicing and expression of AMPA receptors.
Namekata K, Okumura A, Harada C, Nakamura K, Yoshida H, Harada T. Mol Vis. 2006

Role of monocyte chemotactic protein-1 and nuclear factor kappa B in the pathogenesis of proliferative diabetic retinopathy.
Harada C, Okumura A, Namekata K, Nakamura K, Mitamura Y, Ohguro H, Harada T. Diabetes Res Clin Pract. 2006 Dec;74(3):249-56. Epub 2006

Expression of olig2 in retinal progenitor cells.
Nakamura K, Harada C, Namekata K, Harada T. Neuroreport. 2006

Effect of p75NTR on the regulation of photoreceptor apoptosis in the rd mouse.
Nakamura K, Harada C, Okumura A, Namekata K, Mitamura Y, Yoshida K, Ohno S, Yoshida H, Harada T. Mol Vis. 2005

Role of apoptosis signal-regulating kinase 1 in stress-induced neural cell apoptosis in vivo.
Harada C, Nakamura K, Namekata K, Okumura A, Mitamura Y, Iizuka Y, Kashiwagi K, Yoshida K, Ohno S, Matsuzawa A, Tanaka K, Ichijo H, Harada T. Am J Pathol. 2006

The role of cytokines and trophic factors in epiretinal membranes: involvement of signal transduction in glial cells. Harada C, Mitamura Y, Harada T. Prog Retin Eye Res. 2006

Effect of p75NTR on the regulation of naturally occurring cell death and retinal ganglion cell number in the mouse eye.
Harada C, Harada T, Nakamura K, Sakai Y, Tanaka K, Parada LF. Dev Biol. 2006

Activator protein-1 in epiretinal membranes of patients with proliferative diabetic retinopathy.
Mitamura Y, Okumura A, Harada C, Namekata K, Nakamura K, Tashimo A, Ohtsuka K, Harada T. Diabetologia. 2006

Inactivation of NF1 in CNS causes increased glial progenitor proliferation and optic glioma formation.
Zhu Y, Harada T, Liu L, Lush ME, Guignard F, Harada C, Burns DK, Bajenaru ML, Gutmann DH, Parada LF. Development. 2005

Phosphorylation of extracellular signal-regulated kinase and p27(KIP1) after retinal detachment.
Kase S, Yoshida K, Harada T, Harada C, Namekata K, Suzuki Y, Ohgami K, Shiratori K, Nakayama KI, Ohno S. Graefes Arch Clin Exp Ophthalmol. 2006

Disappearance of p27(KIP1) and increase in proliferation of the lens cells after extraction of most of the fiber cells of the lens.
Kase S, Yoshida K, Ikeda H, Harada T, Harada C, Imaki J, Ohgami K, Shiratori K, Nakayama KI, Nakayama K, Ohno S. Curr Eye Res. 2005

Phosphorylation of p27(KIP1) in the developing retina and retinoblastoma.
Kase S, Yoshida K, Nakayama KI, Nakayama K, Ikeda H, Harada T, Harada C, Ohgami K, Shiratori K, Ohno S. Int J Mol Med. 2005

Role of neurotrophin-4/5 in neural cell death during retinal development and ischemic retinal injury in vivo.
Harada C, Harada T, Quah HM, Namekata K, Yoshida K, Ohno S, Tanaka K, Parada LF. Invest Ophthalmol Vis Sci. 2005

Expression of maf-B mRNA in the epithelium around the eyelid closure of the mouse eye at embryonic day 18.
Kase S, Imaki J, Harada T, Harada C, Ohgami K, Shiratori K, Sakai M, Nishi S, Ohno S, Yoshida K. Anat Embryol (Berl). 2004 Dec;209(2):153-6. Epub 2004

Involvement of p27KIP1 in the proliferation of the developing corneal endothelium.
Yoshida K, Kase S, Nakayama K, Nagahama H, Harada T, Ikeda H, Harada C, Imaki J, Ohgami K, Shiratori K, Ilieva IB, Ohno S, Nishi S, Nakayama KI. Invest Ophthalmol Vis Sci. 2004

Activation of nuclear factor-kappa B in the conjunctiva with the epithelial scraping of the mouse cornea and human epidemic keratoconjunctivitis.
Kase S, Aoki K, Harada T, Harada C, Ohgami K, Shiratori K, Nishi S, Ohno S, Yoshida K. Br J Ophthalmol. 2004

Distribution of p27(KIP1), cyclin D1, and proliferating cell nuclear antigen after retinal detachment.
Yoshida K, Kase S, Nakayama K, Nagahama H, Harada T, Ikeda H, Harada C, Imaki J, Ohgami K, Shiratori K, Ohno S, Nakayama KI. Graefes Arch Clin Exp Ophthalmol. 2004 May;242(5):437-41. Epub 2004

Involvement of p27(KIP1) in proliferation of the retinal pigment epithelium and ciliary body.
Yoshida K, Nakayama K, Kase S, Nagahama H, Harada T, Ikeda H, Harada C, Imaki J, Ohgami K, Shiratori K, Ohno S, Nishi S, Nakayama KI. Anat Embryol (Berl). 2004

Diverse NF-kappaB expression in epiretinal membranes after human diabetic retinopathy and proliferative vitreoretinopathy.
Harada C, Harada T, Mitamura Y, Quah HM, Ohtsuka K, Kotake S, Ohno S, Wada K, Takeuchi S, Tanaka K. Mol Vis. 2004

Role of ubiquitin carboxy terminal hydrolase-L1 in neural cell apoptosis induced by ischemic retinal injury in vivo. Harada T, Harada C, Wang YL, Osaka H, Amanai K, Tanaka K, Takizawa S, Setsuie R, Sakurai M, Sato Y, Noda M, Wada K. Am J Pathol. 2004

Potential role of glial cell line-derived neurotrophic factor receptors in Müller glial cells during light-induced retinal degeneration.
Harada C, Harada T, Quah HM, Maekawa F, Yoshida K, Ohno S, Wada K, Parada LF, Tanaka K. Neuroscience. 2003

NF-kappaB in epiretinal membranes after human diabetic retinopathy.
Mitamura Y, Harada T, Harada C, Ohtsuka K, Kotake S, Ohno S, Tanaka K, Takeuchi S, Wada K. Diabetologia. 2003 May;46(5):699-703. Epub 2003 May 13. Erratum in: Diabetologia. 2003

Neurotrophin-3 is required for appropriate establishment of thalamocortical connections.
Ma L, Harada T, Harada C, Romero M, Hebert JM, McConnell SK, Parada LF. Neuron. 2002

Microglia-Müller glia cell interactions control neurotrophic factor production during light-induced retinal degeneration.
Harada T, Harada C, Kohsaka S, Wada E, Yoshida K, Ohno S, Mamada H, Tanaka K, Parada LF, Wada K. J Neurosci. 2002

Neurotrophic factor receptors in epiretinal membranes after human diabetic retinopathy.
Harada T, Harada C, Mitamura Y, Akazawa C, Ohtsuka K, Ohno S, Takeuchi S, Wada K. Diabetes Care. 2002

Proliferation in the posterior region of the lens of c-maf-/- mice.
Yoshida K, Kim JI, Imaki J, Hiromi I, Nishi S, Matsuda H, Harada T, Harada C, Ohno S, Sakai M. Curr Eye Res. 2001

Involvement of p27(KIP1) degradation by Skp2 in the regulation of proliferation in response to wounding of corneal epithelium.
Yoshida K, Nakayama K, Nagahama H, Harada T, Harada C, Imaki J, Matsuda A, Yamamoto K, Ito M, Ohno S, Nakayama K. Invest Ophthalmol Vis Sci. 2002

N-acetylated-alpha-linked-acidic dipeptidase inhibitor has a neuroprotective effect on mouse retinal ganglion cells after pressure-induced ischemia.
Harada C, Harada T, Slusher BS, Yoshida K, Matsuda H, Wada K. Neurosci Lett. 2000

Modification of glial-neuronal cell interactions prevents photoreceptor apoptosis during light-induced retinal degeneration.
Harada T, Harada C, Nakayama N, Okuyama S, Yoshida K, Kohsaka S, Matsuda H, Wada K. Neuron. 2000

Severe optic disc edema without hydrocephalus in neurofibromatosis 2.
Harada T, Sawamura Y, Ohashi T, Harada C, Shinmei Y, Yoshida K, Matsuda H. Jpn J Ophthalmol. 1998

Functions of the two glutamate transporters GLAST and GLT-1 in the retina.
Harada T, Harada C, Watanabe M, Inoue Y, Sakagawa T, Nakayama N, Sasaki S, Okuyama S, Watase K, Wada K, Tanaka K. Proc Natl Acad Sci U S A. 1998

Light-induced retinal degeneration suppresses developmental progression of flip-to-flop alternative splicing in GluR1.
Harada T, Harada C, Sekiguchi M, Wada K. J Neurosci. 1998

A case of bilateral optic neuropathy and recurrent transverse myelopathy associated with perinuclear anti-neutrophil cytoplasmic antibodies (p-ANCA).
Harada T, Ohashi T, Harada C, Yoshida K, Maguchi S, Moriwaka F, Matsuda H. J Neuroophthalmol. 1997