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千歳烏山の眼科クリニック。はらだ眼科です。

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〒157-0062 世田谷区南烏山6-27-10 大黒ビル3階

院長の部屋policy

ロゴマークについて

 
 はらだ眼科のロゴマークを決める際に、私がすぐにイメージしたのは視力検査に使用するランドルト環(アルファベットの「C」のようなマーク)と、フクロウの組み合わせでした。

 日本では当て字で「不苦労」「福朗」などを連想させ、縁起の良い鳥とされているフクロウですが、実は日本だけでなく世界的にも縁起が良いとされています。ギリシャ神話に登場するフクロウは女神アテネの使いとして「森の賢者」と称されるなど知恵と芸術の象徴と伝えられています。アメリカンインディアンは危険を予知する予言者としてフクロウを敬っています。メキシコや中南米では「家や家族を守る」「富の象徴」などとされています。
さらにフクロウの視力は人の20倍とも100倍とも言われています。夜目が利くため、人間にとっては真っ暗な暗闇でもフクロウには夕方程度の暗さのようです。

 皆様に「より良く見える幸福」を感じていただくことが私の使命と考え、縁起が良くて視力も抜群、大きな瞳が愛らしいフクロウを当院のロゴマークに採用しました。

ミッション


安心・納得していただける医療を提供し、「良く見える幸福」を感じていただく

行動指針


1.安全・・・清潔な医療空間、安心と信頼の診察・検査
2.礼儀・・・笑顔とアイコンタクトでさわやかな挨拶
3.平等・・・すべての患者様に同水準の医療サービス
4.合理性・・・患者様の立場にたった迅速かつ丁寧な対応

略歴

院長/医学博士  原田 知加子

平成 7年 北海道大学医学部 卒業
平成7年 北海道大学医学部附属病院 眼科 
平成13年 北海道大学大学院医学研究科 修了 医学博士
平成13年 テキサス大学サウスウエスタンメディカルセンター 博士研究員(上原財団フェロー)
平成14年 東京医科歯科大学 難治疾患研究所 研究員(日本学術振興会特別研究員PD)
平成16年 東京都神経科学総合研究所 研究員(日本学術振興会特別研究員PD,RPD)
平成23年 東京都医学総合研究所 協力研究員(現在も継続中です)
平成24年 はらだ眼科 開院

所属学会


日本眼科学会
北米神経科学会
日本抗加齢医学会

受賞歴

平成19年度 日本眼科学会学術奨励賞 受賞

受賞論文:虚血網膜におけるapoptosis signal-regulating kinase1(ASK1)シグナルの伝達機構と機能解明
Role of apoptosis signal-regulating kinase 1 in stress-induced neural cell apoptosis
in vivo.

第112回日本眼科学会総会にて表彰され、受賞記念講演を行いました。

研究業績New!

大学卒業後は研修医期間を経て大学院へ進学、現在まで一貫して 失明につながる網膜疾患に関する研究を継続しています。


英文の研究業績(1997~2014)

Neurotrophic factors.  
Harada C, Harada T.
In: Neuroprotection and Neuroregeneration for Retinal Diseases. Springer Japan
(Toru Nakazawa, Yasushi Kitaoka, Takayuki Harada, eds.)

Dock3 protects myelin in the cuprizone model for demyelination.
Namekata K, Kimura A, Harada C, Yoshida H, Matsumoto Y, Harada T.Cell Death Dis. (in press)

Dock GEFs and their therapeutic potential: Neuroprotection and axon regeneration.
Namekata K, Kimura A, Kawamura K, Harada C, Harada T. Prog Retin Eye Res. 2014

Brimonidine prevents neurodegeneration in a mouse model of normal tension glaucoma.
Semba K, Namekata K, Kimura A, Harada C, Mitamura Y, Harada T. Cell Death Dis. 2014

Renin-angiotensin system regulates neurodegeneration in a mouse model of normal tension glaucoma.
Semba K, Namekata K, Guo X, Harada C, Harada T, Mitamura Y. Cell Death Dis. 2014

「神経系のMAPキナーゼ」網膜変性疾患とMAPキナーゼ. 
原田知加子、原田高幸. Clinical Neuroscience. 2013

Dock3 attenuates neural cell death due to NMDA neurotoxicity and oxidative stress in a mouse model of normal tension glaucoma.
Namekata K, Kimura A, Kawamura K, Guo X, Harada C, Tanaka K, Harada T. Cell Death Differ. 2013

Inhibition of ASK1-p38 pathway prevents neural cell death following optic nerve injury.
Katome T, Namekata K, Guo X, Semba K, Kittaka D, Kawamura K, Kimura A, Harada C, Ichijo H, Mitamura Y, Harada T. Cell Death Differ. 2013


Expression of promyelocytic leukemia protein and vascular endothelial growth factor in aqueous humor and vitreous fluid in patients with proliferative diabetic retinopathy.
Katome T, Namekata K, Naito T, Semba K, Guo X, Harada C, Harada T, Mitamura Y. Diabetes Res Clin Pract. 2012

Dock3 regulates BDNF-TrkB signaling for neurite outgrowth by forming a ternary complex with Elmo and RhoG. Namekata K, Watanabe H, Guo X, Kittaka D, Kawamura K, Kimura A, Harada C, Harada T. Genes Cells. 2012

Dock3 stimulates axonal outgrowth via GSK-3β-mediated microtubule assembly.
Namekata K, Harada C, Guo X, Kimura A, Kittaka D, Watanabe H, Harada T. J Neurosci. 2012


Expression of promyelocytic leukemia protein and vascular endothelial growth factor in aqueous humor and vitreous fluid in patients with proliferative diabetic retinopathy.Katome T, Namekata K, Naito T, Semba K, Guo X, Harada C, Harada T, Mitamura Y. Diabetes Res Clin Pract. 2012

Glia- and neuron-specific functions of TrkB signalling during retinal degeneration and regeneration.
Harada C, Guo X, Namekata K, Kimura A, Nakamura K, Tanaka K, Parada LF, Harada T. Nat Commun. 2011

Spermidine alleviates severity of murine experimental autoimmune encephalomyelitis.
Guo X, Harada C, Namekata K, Kimura A, Mitamura Y, Yoshida H, Matsumoto Y, Harada T. Invest Ophthalmol Vis Sci. 2011

Regulation of the severity of neuroinflammation and demyelination by TLR-ASK1-p38 pathway.
Guo X, Harada C, Namekata K, Matsuzawa A, Camps M, Ji H, Swinnen D, Jorand-Lebrun C, Muzerelle M, Vitte PA, Rückle T, Kimura A, Kohyama K, Matsumoto Y, Ichijo H, Harada T. EMBO Mol Med. 2010

Delayed onset of experimental autoimmune encephalomyelitis in Olig1 deficient mice.
Guo X, Harada C, Namekata K, Mitamura Y, Yoshida H, Matsumoto Y, Harada T. PLoS One. 2010

ASK1 deficiency attenuates neural cell death in GLAST-deficient mice, a model of normal tension glaucoma.
Harada C, Namekata K, Guo X, Yoshida H, Mitamura Y, Matsumoto Y, Tanaka K, Ichijo H, Harada T. Cell Death Differ. 2010

Dock3 induces axonal outgrowth by stimulating membrane recruitment of the WAVE complex.
Namekata K, Harada C, Taya C, Guo X, Kimura H, Parada LF, Harada T. Proc Natl Acad Sci U S A. 2010

Expression of NG2-positive cells during optic neuritis.
Nakamura K, Guo X, Harada C, Mitamura Y, Matsumoto Y, Harada T. Jpn J Ophthalmol. 2010

Transcription factor, SP1, in epiretinal membranes of patients with proliferative diabetic retinopathy.
Yoshida-Hata N, Mitamura Y, Oshitari T, Namekata K, Harada C, Harada T, Yamamoto S. Diabetes Res Clin Pract. 2010

Interleukin-1 attenuates normal tension glaucoma-like retinal degeneration in EAAC1-deficient mice.
Namekata K, Harada C, Guo X, Kikushima K, Kimura A, Fuse N, Mitamura Y, Kohyama K, Matsumoto Y, Tanaka K, Harada T. Neurosci Lett. 2009 Nov 13;465(2):160-4. Epub 2009

Effect of geranylgeranylacetone on optic neuritis in experimental autoimmune encephalomyelitis.
Guo X, Harada C, Namekata K, Kikushima K, Mitamura Y, Yoshida H, Matsumoto Y, Harada T. Neurosci Lett. 2009

Interleukin-1 stimulates glutamate uptake in glial cells by accelerating membrane trafficking of Na+/K+-ATPase via actin depolymerization.
Namekata K, Harada C, Kohyama K, Matsumoto Y, Harada T. Mol Cell Biol. 2008 May;28(10):3273-80. Epub 2008

Role of cytokines and trophic factors in the pathogenesis of diabetic retinopathy.
Mitamura Y, Harada C, Harada T. Curr Diabetes Rev. 2005

Inhibition of glial cell activation ameliorates the severity of experimental autoimmune encephalomyelitis.
Guo X, Nakamura K, Kohyama K, Harada C, Behanna HA, Watterson DM, Matsumoto Y, Harada T. Neurosci Res. 2007

Neuroprotective effect of geranylgeranylacetone against ischemia-induced retinal injury.
Harada C, Nakamura K, Guo X, Kitaichi N, Mitamura Y, Yoshida K, Ohno S, Yoshida H, Harada T. Mol Vis. 2007

The potential role of glutamate transporters in the pathogenesis of normal tension glaucoma.
Harada T
, Harada C, Nakamura K, Quah HM, Okumura A, Namekata K, Saeki T, Aihara M, Yoshida H, Mitani A, Tanaka K. J Clin Invest. 2007

Glycated albumin induces activation of activator protein-1 in retinal glial cells.
Okumura A, Mitamura Y, Namekata K, Nakamura K, Harada C, Harada T. Jpn J Ophthalmol. 2007

Intracellular sortilin expression pattern regulates proNGF-induced naturally occurring cell death during development. Nakamura K, Namekata K, Harada C, Harada T. Cell Death Differ. 2007 Aug;14(8):1552-4. Epub 2007

Molecular regulation of visual system development: more than meets the eye.
Harada T, Harada C, Parada LF. Genes Dev. 2007

Effect of photoreceptor degeneration on RNA splicing and expression of AMPA receptors.
Namekata K, Okumura A, Harada C, Nakamura K, Yoshida H, Harada T. Mol Vis. 2006

Role of monocyte chemotactic protein-1 and nuclear factor kappa B in the pathogenesis of proliferative diabetic retinopathy.
Harada C
, Okumura A, Namekata K, Nakamura K, Mitamura Y, Ohguro H, Harada T. Diabetes Res Clin Pract. 2006 Dec;74(3):249-56. Epub 2006

Expression of olig2 in retinal progenitor cells.
Nakamura K, Harada C, Namekata K, Harada T. Neuroreport. 2006

Effect of p75NTR on the regulation of photoreceptor apoptosis in the rd mouse.
Nakamura K, Harada C, Okumura A, Namekata K, Mitamura Y, Yoshida K, Ohno S, Yoshida H, Harada T. Mol Vis. 2005

Role of apoptosis signal-regulating kinase 1 in stress-induced neural cell apoptosis in vivo.
Harada C
, Nakamura K, Namekata K, Okumura A, Mitamura Y, Iizuka Y, Kashiwagi K, Yoshida K, Ohno S, Matsuzawa A, Tanaka K, Ichijo H, Harada T. Am J Pathol. 2006

The role of cytokines and trophic factors in epiretinal membranes: involvement of signal transduction in glial cells. Harada C, Mitamura Y, Harada T. Prog Retin Eye Res. 2006

Effect of p75NTR on the regulation of naturally occurring cell death and retinal ganglion cell number in the mouse eye.
Harada C, Harada T, Nakamura K, Sakai Y, Tanaka K, Parada LF. Dev Biol. 2006

Activator protein-1 in epiretinal membranes of patients with proliferative diabetic retinopathy.
Mitamura Y, Okumura A, Harada C, Namekata K, Nakamura K, Tashimo A, Ohtsuka K, Harada T. Diabetologia. 2006

Inactivation of NF1 in CNS causes increased glial progenitor proliferation and optic glioma formation.
Zhu Y, Harada T, Liu L, Lush ME, Guignard F, Harada C, Burns DK, Bajenaru ML, Gutmann DH, Parada LF. Development. 2005

Phosphorylation of extracellular signal-regulated kinase and p27(KIP1) after retinal detachment.
Kase S, Yoshida K, Harada T, Harada C, Namekata K, Suzuki Y, Ohgami K, Shiratori K, Nakayama KI, Ohno S. Graefes Arch Clin Exp Ophthalmol. 2006  

Disappearance of p27(KIP1) and increase in proliferation of the lens cells after extraction of most of the fiber cells of the lens.
Kase S, Yoshida K, Ikeda H, Harada T, Harada C, Imaki J, Ohgami K, Shiratori K, Nakayama KI, Nakayama K, Ohno S. Curr Eye Res. 2005

Phosphorylation of p27(KIP1) in the developing retina and retinoblastoma.
Kase S, Yoshida K, Nakayama KI, Nakayama K, Ikeda H, Harada T, Harada C, Ohgami K, Shiratori K, Ohno S. Int J Mol Med. 2005

Role of neurotrophin-4/5 in neural cell death during retinal development and ischemic retinal injury in vivo.
Harada C
, Harada T, Quah HM, Namekata K, Yoshida K, Ohno S, Tanaka K, Parada LF. Invest Ophthalmol Vis Sci. 2005

Expression of maf-B mRNA in the epithelium around the eyelid closure of the mouse eye at embryonic day 18.
Kase S, Imaki J, Harada T, Harada C, Ohgami K, Shiratori K, Sakai M, Nishi S, Ohno S, Yoshida K. Anat Embryol (Berl). 2004 Dec;209(2):153-6. Epub 2004

Involvement of p27KIP1 in the proliferation of the developing corneal endothelium.
Yoshida K, Kase S, Nakayama K, Nagahama H, Harada T, Ikeda H, Harada C, Imaki J, Ohgami K, Shiratori K, Ilieva IB, Ohno S, Nishi S, Nakayama KI. Invest Ophthalmol Vis Sci. 2004

Activation of nuclear factor-kappa B in the conjunctiva with the epithelial scraping of the mouse cornea and human epidemic keratoconjunctivitis.
Kase S, Aoki K, Harada T, Harada C, Ohgami K, Shiratori K, Nishi S, Ohno S, Yoshida K. Br J Ophthalmol. 2004

Distribution of p27(KIP1), cyclin D1, and proliferating cell nuclear antigen after retinal detachment.
Yoshida K, Kase S, Nakayama K, Nagahama H, Harada T, Ikeda H, Harada C, Imaki J, Ohgami K, Shiratori K, Ohno S, Nakayama KI. Graefes Arch Clin Exp Ophthalmol. 2004 May;242(5):437-41. Epub 2004

Involvement of p27(KIP1) in proliferation of the retinal pigment epithelium and ciliary body.
Yoshida K, Nakayama K, Kase S, Nagahama H, Harada T, Ikeda H, Harada C, Imaki J, Ohgami K, Shiratori K, Ohno S, Nishi S, Nakayama KI. Anat Embryol (Berl). 2004

Diverse NF-kappaB expression in epiretinal membranes after human diabetic retinopathy and proliferative vitreoretinopathy.
Harada C, Harada T, Mitamura Y, Quah HM, Ohtsuka K, Kotake S, Ohno S, Wada K, Takeuchi S, Tanaka K. Mol Vis. 2004

Role of ubiquitin carboxy terminal hydrolase-L1 in neural cell apoptosis induced by ischemic retinal injury in vivo. Harada T, Harada C, Wang YL, Osaka H, Amanai K, Tanaka K, Takizawa S, Setsuie R, Sakurai M, Sato Y, Noda M, Wada K. Am J Pathol. 2004

Potential role of glial cell line-derived neurotrophic factor receptors in Müller glial cells during light-induced retinal degeneration.
Harada C
, Harada T, Quah HM, Maekawa F, Yoshida K, Ohno S, Wada K, Parada LF, Tanaka K. Neuroscience. 2003

NF-kappaB in epiretinal membranes after human diabetic retinopathy.
Mitamura Y, Harada T, Harada C, Ohtsuka K, Kotake S, Ohno S, Tanaka K, Takeuchi S, Wada K. Diabetologia. 2003 May;46(5):699-703. Epub 2003 May 13. Erratum in: Diabetologia. 2003

Neurotrophin-3 is required for appropriate establishment of thalamocortical connections.
Ma L, Harada T, Harada C, Romero M, Hebert JM, McConnell SK, Parada LF. Neuron. 2002

Microglia-Müller glia cell interactions control neurotrophic factor production during light-induced retinal degeneration.
Harada T, Harada C, Kohsaka S, Wada E, Yoshida K, Ohno S, Mamada H, Tanaka K, Parada LF, Wada K. J Neurosci. 2002

Neurotrophic factor receptors in epiretinal membranes after human diabetic retinopathy.
Harada T, Harada C, Mitamura Y, Akazawa C, Ohtsuka K, Ohno S, Takeuchi S, Wada K. Diabetes Care. 2002

Proliferation in the posterior region of the lens of c-maf-/- mice.
Yoshida K, Kim JI, Imaki J, Hiromi I, Nishi S, Matsuda H, Harada T, Harada C, Ohno S, Sakai M. Curr Eye Res. 2001

Involvement of p27(KIP1) degradation by Skp2 in the regulation of proliferation in response to wounding of corneal epithelium.
Yoshida K, Nakayama K, Nagahama H, Harada T, Harada C, Imaki J, Matsuda A, Yamamoto K, Ito M, Ohno S, Nakayama K. Invest Ophthalmol Vis Sci. 2002

N-acetylated-alpha-linked-acidic dipeptidase inhibitor has a neuroprotective effect on mouse retinal ganglion cells after pressure-induced ischemia.
Harada C
, Harada T, Slusher BS, Yoshida K, Matsuda H, Wada K. Neurosci Lett. 2000

Modification of glial-neuronal cell interactions prevents photoreceptor apoptosis during light-induced retinal degeneration.
Harada T, Harada C, Nakayama N, Okuyama S, Yoshida K, Kohsaka S, Matsuda H, Wada K. Neuron. 2000

Severe optic disc edema without hydrocephalus in neurofibromatosis 2.
Harada T, Sawamura Y, Ohashi T, Harada C, Shinmei Y, Yoshida K, Matsuda H. Jpn J Ophthalmol. 1998

Functions of the two glutamate transporters GLAST and GLT-1 in the retina.
Harada T
, Harada C, Watanabe M, Inoue Y, Sakagawa T, Nakayama N, Sasaki S, Okuyama S, Watase K, Wada K, Tanaka K. Proc Natl Acad Sci U S A. 1998

Light-induced retinal degeneration suppresses developmental progression of flip-to-flop alternative splicing in GluR1.
Harada T, Harada C, Sekiguchi M, Wada K. J Neurosci. 1998

A case of bilateral optic neuropathy and recurrent transverse myelopathy associated with perinuclear anti-neutrophil cytoplasmic antibodies (p-ANCA).
Harada T, Ohashi T, Harada C, Yoshida K, Maguchi S, Moriwaka F, Matsuda H. J Neuroophthalmol. 1997



HARADA EYE CLINICはらだ眼科

〒157-0062
東京都世田谷区南烏山6-27-10
大黒ビル3階
TEL 03-5314-0300
FAX 03-5314-0301

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